Raum Lab - Imaging, Simulation & Stimulation 

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12 / 2021

The startup porous GmbH has received one of the most prestigious EU grants to clinically validate the bone microstructure analysis invented in our research group. Our team and the Center for Muscle and Bone Research will support the project and coordinate the planned multicenter prospective validation study.  A big thank you and applause to the entire porous team and all partners who have supported us so far!

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What we do


The main goals of our research group are to combine quantitative imaging with numerical modeling to assess the biomechanical competence of musculoskeletal tissues under normal and pathological conditions. We use the elastic interaction of ultrasonic waves on the one hand to characterize the structure and material properties and on the other hand to promote regeneration. The experiences of our working group lie in the areas of quantitative

  • acoustic microscopy
  • Computed tomography (nano, micro, and high-resolution in-vivo)
  • bone ultrasound
  • multimodal imaging
  • numerical simulation

and the use of ultrasound for regenerative therapies.

An essential aspect of our research activity is the development and application of new examination technologies with the aim of using them to answer specific questions on musculoskeletal systems (bones, cartilage, muscles, cells). Nowadays, the complexity of this discipline requires an effective interaction of various scientific disciplines. The ISS working group is therefore made up of engineers, physicists, physicians, biologists and software developers, which takes into account the interdisciplinary nature of musculoskeletal research. In addition, our laboratory works closely with German and international partner institutes, e.g. in the German-French research network "Ultrasound assessment of bone strength from the tissue level to the organ level".



Zhang H., Beilfuss N., Zabarylo U., Raum K,. & Puts R., (2022)  A Tissue Engineering Acoustophoretic (TEA) Set-up for the Enhanced Osteogenic Differentiation of Murine Mesenchymal Stromal Cells (mMSCs). Int J Mol Sci, 23(19). https://www.ncbi.nlm.nih.gov/pubmed/36232775

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Our team

Our interdisciplinary team combines experts from the fields of physics, medical physics, biochemistry and biotechnology.


You can do your PhD with us in structured programs (BSRT, BIOQIC), in different PhD paths of Charité and our partner universities (Humboldt-Universität Berlin, Technische Universität Berlin).

Are you looking for a research, bachelor, master or PhD thesis? Then send us your application documents including cover letter,curriculum vitae, degree certificates and references. Current job offers can be found here!

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Contact & location

Raum Lab - Imaging, Simulation & Stimulation

Charité - Universitätsmedizin Berlin
Hindenburgdamm 30a, 12203 Berlin

+49 30 450 639 506 

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You can find our internal and external cooperation partners here.