2022
Zhang H., Beilfuss N., Zabarylo U., Raum K,. & Puts R., (2022) A Tissue Engineering Acoustophoretic (TEA) Set-up for the Enhanced Osteogenic Differentiation of Murine Mesenchymal Stromal Cells (mMSCs). Int J Mol Sci, 23(19). https://www.ncbi.nlm.nih.gov/pubmed/36232775
Minh H.N., Muller M. & Raum K. (2022) Estimation of Thickness and Speed of Sound for Transverse Cortical Bone Imaging Using Phase Aberration Correction Methods: An In Silico and Ex Vivo Validation Study. Applied Sciences. 12(10). https://doi.org/10.3390/app12105283
Lye T, Gachouch O., Renner L., Sefer E., Cash, H., Messroghli, D., Raum & Mamou J., (2022) Quantitative Ultrasound Assessment of Early Osteoarthritis in Human Articular Cartilage Using a High-Frequency Linear Array Transducer. Ultrasound Med Biol, doi.org/10.1016/j.ultrasmedbio.2022.03.006
Bortel, E., Grover, L. M., Eisenstein, N., Seim, C., Suhonen, H., Pacureanu, A., Westenberger, P., Raum, K., Langer, M., Peyrin, F., Addison, O., & Hesse, B. (2022). Interconnectivity Explains High Canalicular Network Robustness between Neighboring Osteocyte Lacunae in Human Bone. Advanced Nanobiomed Research, 2(4). https://doi.org/ARTN 2100090
Raum, K., & Laugier, P. (2022). Clinical Devices for Bone Assessment. Adv Exp Med Biol, 1364, 35-53. https://doi.org/10.1007/978-3-030-91979-5_3
2021
Armbrecht, G., Nguyen Minh, H., Massmann, J., & Raum, K. (2021). Pore-Size Distribution and Frequency-Dependent Attenuation in Human Cortical Tibia Bone Discriminate Fragility Fractures in Postmenopausal Women With Low Bone Mineral Density. JBMR Plus, 5(11), e10536. https://doi.org/10.1002/jbm4.10536
Iori, G., Du, J., Hackenbeck, J., Kilappa, V., & Raum, K. (2021). Estimation of Cortical Bone Microstructure From Ultrasound Backscatter. IEEE Trans Ultrason Ferroelectr Freq Control, 68(4), 1081-1095. https://doi.org/10.1109/TUFFC.2020.3033050
Peralta, L., Maeztu Redin, J. D., Fan, F., Cai, X., Laugier, P., Schneider, J., Raum, K., & Grimal, Q. (2021a). Bulk Wave Velocities in Cortical Bone Reflect Porosity and Compression Strength. Ultrasound Med Biol, 47(3), 799-808. https://doi.org/10.1016/j.ultrasmedbio.2020.11.012
Peralta, L., Maeztu Redin, J. D., Fan, F., Cai, X., Laugier, P., Schneider, J., Raum, K., & Grimal, Q. (2021b). Erratum to 'Bulk Wave Velocities in Cortical Bone Reflect Porosity and Compression Strength' [Ultrasound in Med. & Biol. 47 (2021) 799-808]. Ultrasound Med Biol, 47(6), 1637. https://doi.org/10.1016/j.ultrasmedbio.2021.02.017
Puts, R., Vico, R., Beilfuss, N., Shaka, M., Padilla, F., & Raum, K. (2021). Pulsed ultrasound for bone regeneration - outcomes and hurdles in the clinical application: a systematic review. Eur Cell Mater, 41, 281-311. https://doi.org/10.22203/eCM.v042a20
2020
Hocotz, T., Bibikova, O., Belikova, V., Bogomolov, A., Usenov, I., Pieszczek, L., Sakharova, T., Minet, O., Feliksberger, E., Artyushenko, V., Rau, B., & Zabarylo, U. (2020). Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer. Sensors (Basel), 20(22). https://doi.org/10.3390/s20226706
Iori, G., Peralta, L., Reisinger, A., Heyer, F., Wyers, C., van den Bergh, J., Pahr, D., & Raum, K. (2020). Femur strength predictions by nonlinear homogenized voxel finite element models reflect the microarchitecture of the femoral neck. Med Eng Phys, 79, 60-66. https://doi.org/10.1016/j.medengphy.2020.03.005
Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2020). Cortical thinning and accumulation of large cortical pores in the tibia reflect local structural deterioration of the femoral neck. Bone, 137, 115446. https://doi.org/10.1016/j.bone.2020.115446
Nguyen Minh, H., Du, J., & Raum, K. (2020). Estimation of Thickness and Speed of Sound in Cortical Bone Using Multifocus Pulse-Echo Ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control, 67(3), 568-579. https://doi.org/10.1109/TUFFC.2019.2948896
Raimann, A., Mehany, S. N., Feil, P., Weber, M., Pietschmann, P., Boni-Mikats, A., Klepochova, R., Krssak, M., Hausler, G., Schneider, J., Patsch, J. M., & Raum, K. (2020). Decreased Compressional Sound Velocity Is an Indicator for Compromised Bone Stiffness in X-Linked Hypophosphatemic Rickets (XLH). Front Endocrinol (Lausanne), 11, 355. https://doi.org/10.3389/fendo.2020.00355
Stolzel, K., Szczepek, A. J., Olze, H., Koss, S., Minet, O., & Zabarylo, U. (2020). Digital diaphanoscopy of the maxillary sinuses: A revival of optical diagnosis for rhinosinusitis. Am J Otolaryngol, 41(3), 102444. https://doi.org/10.1016/j.amjoto.2020.102444
Zatloukalova, J., & Raum, K. (2020). High frequency ultrasound assesses transient changes in cartilage under osmotic loading. Math Biosci Eng, 17(5), 5190-5211. https://doi.org/10.3934/mbe.2020281
2019
Ehlen, L., Zabarylo, U. J., Speichinger, F., Bogomolov, A., Belikova, V., Bibikova, O., Artyushenko, V., Minet, O., Beyer, K., Kreis, M. E., & Kamphues, C. (2019). Synergy of Fluorescence and Near-Infrared Spectroscopy in Detection of Colorectal Cancer. J Surg Res, 242, 349-356. https://doi.org/10.1016/j.jss.2019.05.011
Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Grasel, M., Barkmann, R., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2019a). Correction: Large cortical bone pores in the tibia are associated with proximal femur strength. PLoS One, 14(7), e0219443. https://doi.org/10.1371/journal.pone.0219443
Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Grasel, M., Barkmann, R., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2019b). Large cortical bone pores in the tibia are associated with proximal femur strength. PLoS One, 14(4), e0215405. https://doi.org/10.1371/journal.pone.0215405
Karbalaeisadegh, Y., Yousefian, O., Iori, G., Raum, K., & Muller, M. (2019). Acoustic diffusion constant of cortical bone: Numerical simulation study of the effect of pore size and pore density on multiple scattering. J Acoust Soc Am, 146(2), 1015. https://doi.org/10.1121/1.5121010
Schneider, J., Iori, G., Ramiandrisoa, D., Hammami, M., Grasel, M., Chappard, C., Barkmann, R., Laugier, P., Grimal, Q., Minonzio, J. G., & Raum, K. (2019). Ex vivo cortical porosity and thickness predictions at the tibia using full-spectrum ultrasonic guided-wave analysis. Arch Osteoporos, 14(1), 21. https://doi.org/10.1007/s11657-019-0578-1
Schneider, J., Ramiandrisoa, D., Armbrecht, G., Ritter, Z., Felsenberg, D., Raum, K., & Minonzio, J. G. (2019). In Vivo Measurements of Cortical Thickness and Porosity at the Proximal Third of the Tibia Using Guided Waves: Comparison with Site-Matched Peripheral Quantitative Computed Tomography and Distal High-Resolution Peripheral Quantitative Computed Tomography. Ultrasound Med Biol, 45(5), 1234-1242. https://doi.org/10.1016/j.ultrasmedbio.2019.01.008
2018
Iori, G., Heyer, F., Kilappa, V., Wyers, C., Varga, P., Schneider, J., Grasel, M., Wendlandt, R., Barkmann, R., van den Bergh, J. P., & Raum, K. (2018). BMD-based assessment of local porosity in human femoral cortical bone. Bone, 114, 50-61. https://doi.org/10.1016/j.bone.2018.05.028
Puts, R., Rikeit, P., Ruschke, K., Knaus, P., Schreivogel, S., & Raum, K. (2018). Functional regulation of YAP mechanosensitive transcriptional coactivator by Focused Low-Intensity Pulsed Ultrasound (FLIPUS) enhances proliferation of murine mesenchymal precursors. PLoS One, 13(10), e0206041. https://doi.org/10.1371/journal.pone.0206041
2017
Bogomolov, A., Belikova, V., Zabarylo, U. J., Bibikova, O., Usenov, I., Sakharova, T., Krause, H., Minet, O., Feliksberger, E., & Artyushenko, V. (2017). Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics. Sensors (Basel), 17(11). https://doi.org/10.3390/s17112548
Bogomolov, A., Zabarylo, U., Kirsanov, D., Belikova, V., Ageev, V., Usenov, I., Galyanin, V., Minet, O., Sakharova, T., Danielyan, G., Feliksberger, E., & Artyushenko, V. (2017). Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics. Sensors (Basel), 17(8). https://doi.org/10.3390/s17081914
Gelse, K., Korber, L., Schone, M., Raum, K., Koch, P., Pachowsky, M., Welsch, G., & Breiter, R. (2017). Transplantation of Chemically Processed Decellularized Meniscal Allografts. Cartilage, 8(2), 180-190. https://doi.org/10.1177/1947603516646161
Potsika, V. T., Protopappas, V. C., Grivas, K. N., Gortsas, T. V., Raum, K., Polyzos, D. K., & Fotiadis, D. I. (2017). Numerical evaluation of the backward propagating acoustic field in healing long bones. J Acoust Soc Am, 142(2), 962. https://doi.org/10.1121/1.4998722
Rohrbach, D., Inkinen, S. I., Zatloukalova, J., Kadow-Romacker, A., Joukainen, A., Malo, M. K., Mamou, J., Toyras, J., & Raum, K. (2017). Regular chondrocyte spacing is a potential cause for coherent ultrasound backscatter in human articular cartilage. J Acoust Soc Am, 141(5), 3105. https://doi.org/10.1121/1.4979339
Schone, M., Schulz, R. M., Tzschatzsch, H., Varga, P., & Raum, K. (2017). Ultrasound palpation for fast in-situ quantification of articular cartilage stiffness, thickness and relaxation capacity. Biomech Model Mechanobiol, 16(4), 1171-1185. https://doi.org/10.1007/s10237-017-0880-z
2016
Bernard, S., Schneider, J., Varga, P., Laugier, P., Raum, K., & Grimal, Q. (2016). Elasticity-density and viscoelasticity-density relationships at the tibia mid-diaphysis assessed from resonant ultrasound spectroscopy measurements. Biomech Model Mechanobiol, 15(1), 97-109. https://doi.org/10.1007/s10237-015-0689-6
Hesse, B., Salome, M., Castillo-Michel, H., Cotte, M., Fayard, B., Sahle, C. J., De Nolf, W., Hradilova, J., Masic, A., Kanngiesser, B., Bohner, M., Varga, P., Raum, K., & Schrof, S. (2016). Full-Field Calcium K-Edge X-ray Absorption Near-Edge Structure Spectroscopy on Cortical Bone at the Micron-Scale: Polarization Effects Reveal Mineral Orientation. Anal Chem, 88(7), 3826-3835. https://doi.org/10.1021/acs.analchem.5b04898
Mannicke, N., Schone, M., Liukkonen, J., Fachet, D., Inkinen, S., Malo, M. K., Oelze, M. L., Toyras, J., Jurvelin, J. S., & Raum, K. (2016). Species-Independent Modeling of High-Frequency Ultrasound Backscatter in Hyaline Cartilage. Ultrasound Med Biol, 42(6), 1375-1384. https://doi.org/10.1016/j.ultrasmedbio.2016.01.018
Padilla, F., Puts, R., Vico, L., Guignandon, A., & Raum, K. (2016). Stimulation of Bone Repair with Ultrasound. Adv Exp Med Biol, 880, 385-427. https://doi.org/10.1007/978-3-319-22536-4_21
Penta, R., Raum, K., Grimal, Q., Schrof, S., & Gerisch, A. (2016). Can a continuous mineral foam explain the stiffening of aged bone tissue? A micromechanical approach to mineral fusion in musculoskeletal tissues. Bioinspir Biomim, 11(3), 035004. https://doi.org/10.1088/1748-3190/11/3/035004
Puts, R., Albers, J., Kadow-Romacker, A., Geissler, S., & Raum, K. (2016). Influence of Donor Age and Stimulation Intensity on Osteogenic Differentiation of Rat Mesenchymal Stromal Cells in Response to Focused Low-Intensity Pulsed Ultrasound. Ultrasound Med Biol, 42(12), 2965-2974. https://doi.org/10.1016/j.ultrasmedbio.2016.08.012
Puts, R., Rikeit, P., Ruschke, K., Kadow-Romacker, A., Hwang, S., Jenderka, K. V., Knaus, P., & Raum, K. (2016). Activation of Mechanosensitive Transcription Factors in Murine C2C12 Mesenchymal Precursors by Focused Low-Intensity Pulsed Ultrasound (FLIPUS). IEEE Trans Ultrason Ferroelectr Freq Control, 63(10), 1505-1513. https://doi.org/10.1109/TUFFC.2016.2586972
Puts, R., Ruschke, K., Ambrosi, T. H., Kadow-Romacker, A., Knaus, P., Jenderka, K. V., & Raum, K. (2016). A Focused Low-Intensity Pulsed Ultrasound (FLIPUS) System for Cell Stimulation: Physical and Biological Proof of Principle. IEEE Trans Ultrason Ferroelectr Freq Control, 63(1), 91-100. https://doi.org/10.1109/TUFFC.2015.2498042
Schone, M., Mannicke, N., Somerson, J. S., Marquass, B., Henkelmann, R., Mochida, J., Aigner, T., Raum, K., & Schulz, R. M. (2016). 3D ultrasound biomicroscopy for assessment of cartilage repair tissue: volumetric characterisation and correlation to established classification systems. Eur Cell Mater, 31, 119-135. https://doi.org/10.22203/ecm.v031a09
Schrof, S., Varga, P., Hesse, B., Schone, M., Schutz, R., Masic, A., & Raum, K. (2016). Multimodal correlative investigation of the interplaying micro-architecture, chemical composition and mechanical properties of human cortical bone tissue reveals predominant role of fibrillar organization in determining microelastic tissue properties. Acta Biomater, 44, 51-64. https://doi.org/10.1016/j.actbio.2016.08.001
Potsika, V., Gortsas, T., Iori, G., V, C. P., Raum, K., Polyzos, D., & D, I. F. (2016). Computational Study of the Effect of Cortical Porosity on Ultrasound Wave Propagation in Healthy and Osteoporotic Long Bones. Materials (Basel), 9(3). https://doi.org/10.3390/ma9030205
2015
Amitai, I., Werner, S., Schicke, B., Burmester, G. R., Minet, O., Zabarylo, U., Backhaus, M., & Ohrndorf, S. (2015). Comparison of Photo Optical Imaging with Musculoskeletal Ultrasound and Clinical Examination in the Assessment of Inflammatory Activity in Proximal Interphalangeal Joints in Rheumatoid Arthritis and Osteoarthritis. J Rheumatol, 42(9), 1595-1602. https://doi.org/10.3899/jrheum.150098
Bernal, A., Perez, L. M., De Lucas, B., Martin, N. S., Kadow-Romacker, A., Plaza, G., Raum, K., & Galvez, B. G. (2015). Low-Intensity Pulsed Ultrasound Improves the Functional Properties of Cardiac Mesoangioblasts. Stem Cell Rev Rep, 11(6), 852-865. https://doi.org/10.1007/s12015-015-9608-6
Checa, S., Hesse, B., Roschger, P., Aido, M., Duda, G. N., Raum, K., & Willie, B. M. (2015). Skeletal maturation substantially affects elastic tissue properties in the endosteal and periosteal regions of loaded mice tibiae. Acta Biomater, 21, 154-164. https://doi.org/10.1016/j.actbio.2015.04.020
Granke, M., Grimal, Q., Parnell, W. J., Raum, K., Gerisch, A., Peyrin, F., Saied, A., & Laugier, P. (2015). To what extent can cortical bone millimeter-scale elasticity be predicted by a two-phase composite model with variable porosity? Acta Biomater, 12, 207-215. https://doi.org/10.1016/j.actbio.2014.10.011
Hesse, B., Varga, P., Langer, M., Pacureanu, A., Schrof, S., Mannicke, N., Suhonen, H., Maurer, P., Cloetens, P., Peyrin, F., & Raum, K. (2015). Canalicular network morphology is the major determinant of the spatial distribution of mass density in human bone tissue: evidence by means of synchrotron radiation phase-contrast nano-CT. J Bone Miner Res, 30(2), 346-356. https://doi.org/10.1002/jbmr.2324
Potsika, V. T., Grivas, K. N., Gortsas, T., Protopappas, V. C., Polyzos, D. K., Raum, K., & Fotiadis, D. I. (2015). Ultrasound propagation in cortical bone: Axial transmission and backscattering simulations. Annu Int Conf IEEE Eng Med Biol Soc, 2015, 1456-1459. https://doi.org/10.1109/EMBC.2015.7318644
Rohrbach, D., Grimal, Q., Varga, P., Peyrin, F., Langer, M., Laugier, P., & Raum, K. (2015). Distribution of mesoscale elastic properties and mass density in the human femoral shaft. Connect Tissue Res, 56(2), 120-132. https://doi.org/10.3109/03008207.2015.1013627
Varga, P., Hesse, B., Langer, M., Schrof, S., Mannicke, N., Suhonen, H., Pacureanu, A., Pahr, D., Peyrin, F., & Raum, K. (2015). Synchrotron X-ray phase nano-tomography-based analysis of the lacunar-canalicular network morphology and its relation to the strains experienced by osteocytes in situ as predicted by case-specific finite element analysis. Biomech Model Mechanobiol, 14(2), 267-282. https://doi.org/10.1007/s10237-014-0601-9
2014
Grimal, Q., Rohrbach, D., Grondin, J., Barkmann, R., Gluer, C. C., Raum, K., & Laugier, P. (2014). Modeling of femoral neck cortical bone for the numerical simulation of ultrasound propagation. Ultrasound Med Biol, 40(5), 1015-1026. https://doi.org/10.1016/j.ultrasmedbio.2013.11.010
Hesse, B., Langer, M., Varga, P., Pacureanu, A., Dong, P., Schrof, S., Mannicke, N., Suhonen, H., Olivier, C., Maurer, P., Kazakia, G. J., Raum, K., & Peyrin, F. (2014). Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron microCT study. PLoS One, 9(2), e88481. https://doi.org/10.1371/journal.pone.0088481
Hesse, B., Mannicke, N., Pacureanu, A., Varga, P., Langer, M., Maurer, P., Peyrin, F., & Raum, K. (2014). Accessing osteocyte lacunar geometrical properties in human jaw bone on the submicron length scale using synchrotron radiation muCT. J Microsc, 255(3), 158-168. https://doi.org/10.1111/jmi.12147
Kuhnisch, J., Seto, J., Lange, C., Schrof, S., Stumpp, S., Kobus, K., Grohmann, J., Kossler, N., Varga, P., Osswald, M., Emmerich, D., Tinschert, S., Thielemann, F., Duda, G., Seifert, W., El Khassawna, T., Stevenson, D. A., Elefteriou, F., Kornak, U., Kolanczyk, M. (2014). Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1. PLoS One, 9(1), e86115. https://doi.org/10.1371/journal.pone.0086115
Langer, M., Cloetens, P., Hesse, B., Suhonen, H., Pacureanu, A., Raum, K., & Peyrin, F. (2014). Priors for X-ray in-line phase tomography of heterogeneous objects. Philos Trans A Math Phys Eng Sci, 372(2010), 20130129. https://doi.org/10.1098/rsta.2013.0129
Mannicke, N., Schone, M., Gottwald, M., Gobel, F., Oelze, M. L., & Raum, K. (2014). 3-D high-frequency ultrasound backscatter analysis of human articular cartilage. Ultrasound Med Biol, 40(1), 244-257. https://doi.org/10.1016/j.ultrasmedbio.2013.08.015
Mannicke, N., Schone, M., Oelze, M., & Raum, K. (2014). Articular cartilage degeneration classification by means of high-frequency ultrasound. Osteoarthritis Cartilage, 22(10), 1577-1582. https://doi.org/10.1016/j.joca.2014.06.019
Padilla, F., Puts, R., Vico, L., & Raum, K. (2014). Stimulation of bone repair with ultrasound: a review of the possible mechanic effects. Ultrasonics, 54(5), 1125-1145. https://doi.org/10.1016/j.ultras.2014.01.004
Petter-Puchner, A., Gruber-Blum, S., Walder, N., Fortelny, R. H., Redl, H., & Raum, K. (2014). Ultrasound biomicroscopy (UBM) and scanning acoustic microscopy (SAM) for the assessment of hernia mesh integration: a comparison to standard histology in an experimental model. Hernia, 18(4), 579-585. https://doi.org/10.1007/s10029-013-1201-9
Potsika, V. T., Grivas, K. N., Protopappas, V. C., Vavva, M. G., Raum, K., Rohrbach, D., Polyzos, D., & Fotiadis, D. I. (2014). Application of an effective medium theory for modeling ultrasound wave propagation in healing long bones. Ultrasonics, 54(5), 1219-1230. https://doi.org/10.1016/j.ultras.2013.09.002
Raum, K., Grimal, Q., Varga, P., Barkmann, R., Gluer, C. C., & Laugier, P. (2014). Ultrasound to assess bone quality. Curr Osteoporos Rep, 12(2), 154-162. https://doi.org/10.1007/s11914-014-0205-4
Rohde, K., Rohrbach, D., Gluer, C. C., Laugier, P., Grimal, Q., Raum, K., & Barkmann, R. (2014). Influence of porosity, pore size, and cortical thickness on the propagation of ultrasonic waves guided through the femoral neck cortex: a simulation study. IEEE Trans Ultrason Ferroelectr Freq Control, 61(2), 302-313. https://doi.org/10.1109/TUFFC.2014.6722615
Schrof, S., Varga, P., Galvis, L., Raum, K., & Masic, A. (2014). 3D Raman mapping of the collagen fibril orientation in human osteonal lamellae. J Struct Biol, 187(3), 266-275. https://doi.org/10.1016/j.jsb.2014.07.001
Tiburtius, S., Schrof, S., Molnar, F., Varga, P., Peyrin, F., Grimal, Q., Raum, K., & Gerisch, A. (2014). On the elastic properties of mineralized turkey leg tendon tissue: multiscale model and experiment. Biomech Model Mechanobiol, 13(5), 1003-1023. https://doi.org/10.1007/s10237-013-0550-8
2013
Granke, M., Gourrier, A., Rupin, F., Raum, K., Peyrin, F., Burghammer, M., Saied, A., & Laugier, P. (2013). Microfibril orientation dominates the microelastic properties of human bone tissue at the lamellar length scale. PLoS One, 8(3), e58043. https://doi.org/10.1371/journal.pone.0058043
Malo, M. K., Rohrbach, D., Isaksson, H., Toyras, J., Jurvelin, J. S., Tamminen, I. S., Kroger, H., & Raum, K. (2013). Longitudinal elastic properties and porosity of cortical bone tissue vary with age in human proximal femur. Bone, 53(2), 451-458. https://doi.org/10.1016/j.bone.2013.01.015
Rohrbach, D., Preininger, B., Hesse, B., Gerigk, H., Perka, C., & Raum, K. (2013). The early phases of bone healing can be differentiated in a rat osteotomy model by focused transverse-transmission ultrasound. Ultrasound Med Biol, 39(9), 1642-1653. https://doi.org/10.1016/j.ultrasmedbio.2013.03.028
Schone, M., Mannicke, N., Gottwald, M., Gobel, F., & Raum, K. (2013). 3-d high-frequency ultrasound improves the estimation of surface properties in degenerated cartilage. Ultrasound Med Biol, 39(5), 834-844. https://doi.org/10.1016/j.ultrasmedbio.2012.10.010
Varga, P., Pacureanu, A., Langer, M., Suhonen, H., Hesse, B., Grimal, Q., Cloetens, P., Raum, K., & Peyrin, F. (2013). Investigation of the three-dimensional orientation of mineralized collagen fibrils in human lamellar bone using synchrotron X-ray phase nano-tomography. Acta Biomater, 9(9), 8118-8127. https://doi.org/10.1016/j.actbio.2013.05.015
2012
Lakshmanan, S., Koch, T., Brand, S., Mannicke, N., Wicke, M., Morlein, D., & Raum, K. (2012). Prediction of the intramuscular fat content in loin muscle of pig carcasses by quantitative time-resolved ultrasound. Meat Sci, 90(1), 216-225. https://doi.org/10.1016/j.meatsci.2011.07.004
Preininger, B., Hesse, B., Rohrbach, D., Varga, P., Gerigk, H., Langer, M., Peyrin, F., Perka, C., & Raum, K. (2012). Histogram feature-based classification improves differentiability of early bone healing stages from micro-computed tomographic data. J Comput Assist Tomogr, 36(4), 469-476. https://doi.org/10.1097/RCT.0b013e31825eae8a
Rohrbach, D., Lakshmanan, S., Peyrin, F., Langer, M., Gerisch, A., Grimal, Q., Laugier, P., & Raum, K. (2012). Spatial distribution of tissue level properties in a human femoral cortical bone. J Biomech, 45(13), 2264-2270. https://doi.org/10.1016/j.jbiomech.2012.06.003
2011
Grimal, Q., Raum, K., Gerisch, A., & Laugier, P. (2011). A determination of the minimum sizes of representative volume elements for the prediction of cortical bone elastic properties. Biomech Model Mechanobiol, 10(6), 925-937. https://doi.org/10.1007/s10237-010-0284-9
Koch, T., Lakshmanan, S., Brand, S., Wicke, M., Raum, K., & Morlein, D. (2011a). Ultrasound velocity and attenuation of porcine soft tissues with respect to structure and composition: I. Muscle. Meat Sci, 88(1), 51-58. https://doi.org/10.1016/j.meatsci.2010.12.002
Koch, T., Lakshmanan, S., Brand, S., Wicke, M., Raum, K., & Morlein, D. (2011b). Ultrasound velocity and attenuation of porcine soft tissues with respect to structure and composition: II. Skin and backfat. Meat Sci, 88(1), 67-74. https://doi.org/10.1016/j.meatsci.2010.12.004
Preininger, B., Checa, S., Molnar, F. L., Fratzl, P., Duda, G. N., & Raum, K. (2011). Spatial-temporal mapping of bone structural and elastic properties in a sheep model following osteotomy. Ultrasound Med Biol, 37(3), 474-483. https://doi.org/10.1016/j.ultrasmedbio.2010.12.007
2010
Gelse, K., Olk, A., Eichhorn, S., Swoboda, B., Schoene, M., & Raum, K. (2010). Quantitative ultrasound biomicroscopy for the analysis of healthy and repair cartilage tissue. Eur Cell Mater, 19, 58-71. https://doi.org/10.22203/ecm.v019a07
Minet, O., Scheibe, P., & Zabarylo, U. J. (2010). Diagnosis of rheumatoid arthritis using light: correction of motion artefacts and color visualization of multispectral images. J Biophotonics, 3(3), 130-137. https://doi.org/10.1002/jbio.200900092
Rupin, F., Bossis, D., Vico, L., Peyrin, F., Raum, K., Laugier, P., & Saied, A. (2010). Adaptive remodeling of trabecular bone core cultured in 3-D bioreactor providing cyclic loading: an acoustic microscopy study. Ultrasound Med Biol, 36(6), 999-1007. https://doi.org/10.1016/j.ultrasmedbio.2010.03.004
1998 – 2009
Ruschke, K., Ebelt, H., Kloting, N., Boettger, T., Raum, K., Bluher, M., & Braun, T. (2009). Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice. PLoS One, 4(5), e5516. https://doi.org/10.1371/journal.pone.0005516
Grimal, Q., Raum, K., Gerisch, A., & Laugier, P. (2008). Derivation of the mesoscopic elasticity tensor of cortical bone from quantitative impedance images at the micron scale. Comput Methods Biomech Biomed Engin, 11(2), 147-157. https://doi.org/10.1080/10255840802296913
Leicht, S., & Raum, K. (2008). Acoustic impedance changes in cartilage and subchondral bone due to primary arthrosis. Ultrasonics, 48(6-7), 613-620. https://doi.org/10.1016/j.ultras.2008.04.012
Raum, K. (2008). Microelastic imaging of bone. IEEE Trans Ultrason Ferroelectr Freq Control, 55(7), 1417-1431. https://doi.org/10.1109/TUFFC.2008.817
Saied, A., Raum, K., Leguerney, I., & Laugier, P. (2008). Spatial distribution of anisotropic acoustic impedance assessed by time-resolved 50-MHz scanning acoustic microscopy and its relation to porosity in human cortical bone. Bone, 43(1), 187-194. https://doi.org/10.1016/j.bone.2008.02.015
Lakshmanan, S., Bodi, A., & Raum, K. (2007). Assessment of anisotropic tissue elasticity of cortical bone from high-resolution, angular acoustic measurements. IEEE Trans Ultrason Ferroelectr Freq Control, 54(8), 1560-1570. https://doi.org/10.1109/tuffc.2007.426
Raum, K., Hofmann, T., Leguerney, I., Saied, A., Peyrin, F., Vico, L., & Laugier, P. (2007). Variations of microstructure, mineral density and tissue elasticity in B6/C3H mice. Bone, 41(6), 1017-1024. https://doi.org/10.1016/j.bone.2007.08.042
Raum, K., Kempf, K., Hein, H. J., Schubert, J., & Maurer, P. (2007). Preservation of microelastic properties of dentin and tooth enamel in vitro--a scanning acoustic microscopy study. Dent Mater, 23(10), 1221-1228. https://doi.org/10.1016/j.dental.2006.11.009
Hofman, T., Raum, K., Leguerney, I., Saied, A., Peyrin, F., Vico, L., & Laugier, P. (2006). Assessment of bone structure and acoustic impedance in C3H and BL6 mice using high resolution scanning acoustic microscopy. Ultrasonics, 44 Suppl 1, e1307-1311. https://doi.org/10.1016/j.ultras.2006.05.032
Hofmann, T., Heyroth, F., Meinhard, H., Franzel, W., & Raum, K. (2006). Assessment of composition and anisotropic elastic properties of secondary osteon lamellae. J Biomech, 39(12), 2282-2294. https://doi.org/10.1016/j.jbiomech.2005.07.009
Hube, R., Mayr, H., Hein, W., & Raum, K. (2006). Prediction of biomechanical stability after callus distraction by high resolution scanning acoustic microscopy. Ultrasound Med Biol, 32(12), 1913-1921. https://doi.org/10.1016/j.ultrasmedbio.2006.06.010
Raum, K., Leguerney, I., Chandelier, F., Talmant, M., Saied, A., Peyrin, F., & Laugier, P. (2006). Site-matched assessment of structural and tissue properties of cortical bone using scanning acoustic microscopy and synchrotron radiation muCT. Phys Med Biol, 51(3), 733-746. https://doi.org/10.1088/0031-9155/51/3/017
Raum, K., Cleveland, R. O., Peyrin, F., & Laugier, P. (2006). Derivation of elastic stiffness from site-matched mineral density and acoustic impedance maps. Phys Med Biol, 51(3), 747-758. https://doi.org/10.1088/0031-9155/51/3/018
Raum, K., Leguerney, I., Chandelier, F., Bossy, E., Talmant, M., Saied, A., Peyrin, F., & Laugier, P. (2005). Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements. Ultrasound Med Biol, 31(9), 1225-1235. https://doi.org/10.1016/j.ultrasmedbio.2005.05.002
Raum, K., Reisshauer, J., & Brandt, J. (2004). Frequency and resolution dependence of the anisotropic impedance estimation in cortical bone using time-resolved scanning acoustic microscopy. J Biomed Mater Res A, 71(3), 430-438. https://doi.org/10.1002/jbm.a.30156
Raum, K., Ozguler, A., Morris, S. A., & O'Brien, W. R. (1998). Channel defect detection in food packages using integrated backscatter ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control, 45(1), 30-40. https://doi.org/10.1109/58.646905