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Publikationen

Hier finden Sie die in Fachjournalen mit peer-review" publizierten Arbeiten der AG Raum.

2022

Zhang H., Beilfuss N., Zabarylo U., Raum K,. & Puts R., (2022)  A Tissue Engineering Acoustophoretic (TEA) Set-up for the Enhanced Osteogenic Differentiation of Murine Mesenchymal Stromal Cells (mMSCs). Int J Mol Sci, 23(19). https://www.ncbi.nlm.nih.gov/pubmed/36232775

Minh H.N., Muller M. & Raum K. (2022) Estimation of Thickness and Speed of Sound for Transverse Cortical Bone Imaging Using Phase Aberration Correction Methods: An In Silico and Ex Vivo Validation Study. Applied Sciences. 12(10). https://doi.org/10.3390/app12105283 

Lye T., Gachouch O., Renner L., Sefer E., Cash, H., Messroghli, D., Raum & Mamou J., (2022) Quantitative Ultrasound Assessment of Early Osteoarthritis in Human Articular Cartilage Using a High-Frequency Linear Array Transducer. Ultrasound Med Biol, doi.org/10.1016/j.ultrasmedbio.2022.03.006

Bortel, E., Grover, L. M., Eisenstein, N., Seim, C., Suhonen, H., Pacureanu, A., Westenberger, P., Raum, K., Langer, M., Peyrin, F., Addison, O., & Hesse, B. (2022). Interconnectivity Explains High Canalicular Network Robustness between Neighboring Osteocyte Lacunae in Human Bone. Advanced Nanobiomed Research, 2(4). https://doi.org/ARTN 2100090

Raum, K., & Laugier, P. (2022). Clinical Devices for Bone Assessment. Adv Exp Med Biol, 1364, 35-53. https://doi.org/10.1007/978-3-030-91979-5_3

 

2021

Armbrecht, G., Nguyen Minh, H., Massmann, J., & Raum, K. (2021). Pore-Size Distribution and Frequency-Dependent Attenuation in Human Cortical Tibia Bone Discriminate Fragility Fractures in Postmenopausal Women With Low Bone Mineral Density. JBMR Plus, 5(11), e10536. https://doi.org/10.1002/jbm4.10536

Iori, G., Du, J., Hackenbeck, J., Kilappa, V., & Raum, K. (2021). Estimation of Cortical Bone Microstructure From Ultrasound Backscatter. IEEE Trans Ultrason Ferroelectr Freq Control, 68(4), 1081-1095. https://doi.org/10.1109/TUFFC.2020.3033050

Peralta, L., Maeztu Redin, J. D., Fan, F., Cai, X., Laugier, P., Schneider, J., Raum, K., & Grimal, Q. (2021a). Bulk Wave Velocities in Cortical Bone Reflect Porosity and Compression Strength. Ultrasound Med Biol, 47(3), 799-808. https://doi.org/10.1016/j.ultrasmedbio.2020.11.012

Peralta, L., Maeztu Redin, J. D., Fan, F., Cai, X., Laugier, P., Schneider, J., Raum, K., & Grimal, Q. (2021b). Erratum to 'Bulk Wave Velocities in Cortical Bone Reflect Porosity and Compression Strength' [Ultrasound in Med. & Biol. 47 (2021) 799-808]. Ultrasound Med Biol, 47(6), 1637. https://doi.org/10.1016/j.ultrasmedbio.2021.02.017

Puts, R., Vico, R., Beilfuss, N., Shaka, M., Padilla, F., & Raum, K. (2021). Pulsed ultrasound for bone regeneration - outcomes and hurdles in the clinical application: a systematic review. Eur Cell Mater, 41, 281-311. https://doi.org/10.22203/eCM.v042a20

 

2020

Hocotz, T., Bibikova, O., Belikova, V., Bogomolov, A., Usenov, I., Pieszczek, L., Sakharova, T., Minet, O., Feliksberger, E., Artyushenko, V., Rau, B., & Zabarylo, U. (2020). Synergy Effect of Combined Near and Mid-Infrared Fibre Spectroscopy for Diagnostics of Abdominal Cancer. Sensors (Basel), 20(22). https://doi.org/10.3390/s20226706

Iori, G., Peralta, L., Reisinger, A., Heyer, F., Wyers, C., van den Bergh, J., Pahr, D., & Raum, K. (2020). Femur strength predictions by nonlinear homogenized voxel finite element models reflect the microarchitecture of the femoral neck. Med Eng Phys, 79, 60-66. https://doi.org/10.1016/j.medengphy.2020.03.005

Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2020). Cortical thinning and accumulation of large cortical pores in the tibia reflect local structural deterioration of the femoral neck. Bone, 137, 115446. https://doi.org/10.1016/j.bone.2020.115446

Nguyen Minh, H., Du, J., & Raum, K. (2020). Estimation of Thickness and Speed of Sound in Cortical Bone Using Multifocus Pulse-Echo Ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control, 67(3), 568-579. https://doi.org/10.1109/TUFFC.2019.2948896

Raimann, A., Mehany, S. N., Feil, P., Weber, M., Pietschmann, P., Boni-Mikats, A., Klepochova, R., Krssak, M., Hausler, G., Schneider, J., Patsch, J. M., & Raum, K. (2020). Decreased Compressional Sound Velocity Is an Indicator for Compromised Bone Stiffness in X-Linked Hypophosphatemic Rickets (XLH). Front Endocrinol (Lausanne), 11, 355. https://doi.org/10.3389/fendo.2020.00355

Stolzel, K., Szczepek, A. J., Olze, H., Koss, S., Minet, O., & Zabarylo, U. (2020). Digital diaphanoscopy of the maxillary sinuses: A revival of optical diagnosis for rhinosinusitis. Am J Otolaryngol, 41(3), 102444. https://doi.org/10.1016/j.amjoto.2020.102444

Zatloukalova, J., & Raum, K. (2020). High frequency ultrasound assesses transient changes in cartilage under osmotic loading. Math Biosci Eng, 17(5), 5190-5211. https://doi.org/10.3934/mbe.2020281

 

2019

Ehlen, L., Zabarylo, U. J., Speichinger, F., Bogomolov, A., Belikova, V., Bibikova, O., Artyushenko, V., Minet, O., Beyer, K., Kreis, M. E., & Kamphues, C. (2019). Synergy of Fluorescence and Near-Infrared Spectroscopy in Detection of Colorectal Cancer. J Surg Res, 242, 349-356. https://doi.org/10.1016/j.jss.2019.05.011

Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Grasel, M., Barkmann, R., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2019a). Correction: Large cortical bone pores in the tibia are associated with proximal femur strength. PLoS One, 14(7), e0219443. https://doi.org/10.1371/journal.pone.0219443

Iori, G., Schneider, J., Reisinger, A., Heyer, F., Peralta, L., Wyers, C., Grasel, M., Barkmann, R., Gluer, C. C., van den Bergh, J. P., Pahr, D., & Raum, K. (2019b). Large cortical bone pores in the tibia are associated with proximal femur strength. PLoS One, 14(4), e0215405. https://doi.org/10.1371/journal.pone.0215405

Karbalaeisadegh, Y., Yousefian, O., Iori, G., Raum, K., & Muller, M. (2019). Acoustic diffusion constant of cortical bone: Numerical simulation study of the effect of pore size and pore density on multiple scattering. J Acoust Soc Am, 146(2), 1015. https://doi.org/10.1121/1.5121010

Schneider, J., Iori, G., Ramiandrisoa, D., Hammami, M., Grasel, M., Chappard, C., Barkmann, R., Laugier, P., Grimal, Q., Minonzio, J. G., & Raum, K. (2019). Ex vivo cortical porosity and thickness predictions at the tibia using full-spectrum ultrasonic guided-wave analysis. Arch Osteoporos, 14(1), 21. https://doi.org/10.1007/s11657-019-0578-1

Schneider, J., Ramiandrisoa, D., Armbrecht, G., Ritter, Z., Felsenberg, D., Raum, K., & Minonzio, J. G. (2019). In Vivo Measurements of Cortical Thickness and Porosity at the Proximal Third of the Tibia Using Guided Waves: Comparison with Site-Matched Peripheral Quantitative Computed Tomography and Distal High-Resolution Peripheral Quantitative Computed Tomography. Ultrasound Med Biol, 45(5), 1234-1242. https://doi.org/10.1016/j.ultrasmedbio.2019.01.008

 

2018

Iori, G., Heyer, F., Kilappa, V., Wyers, C., Varga, P., Schneider, J., Grasel, M., Wendlandt, R., Barkmann, R., van den Bergh, J. P., & Raum, K. (2018). BMD-based assessment of local porosity in human femoral cortical bone. Bone, 114, 50-61. https://doi.org/10.1016/j.bone.2018.05.028

Puts, R., Rikeit, P., Ruschke, K., Knaus, P., Schreivogel, S., & Raum, K. (2018). Functional regulation of YAP mechanosensitive transcriptional coactivator by Focused Low-Intensity Pulsed Ultrasound (FLIPUS) enhances proliferation of murine mesenchymal precursors. PLoS One, 13(10), e0206041. https://doi.org/10.1371/journal.pone.0206041

 

2017

Bogomolov, A., Belikova, V., Zabarylo, U. J., Bibikova, O., Usenov, I., Sakharova, T., Krause, H., Minet, O., Feliksberger, E., & Artyushenko, V. (2017). Synergy Effect of Combining Fluorescence and Mid Infrared Fiber Spectroscopy for Kidney Tumor Diagnostics. Sensors (Basel), 17(11). https://doi.org/10.3390/s17112548

Bogomolov, A., Zabarylo, U., Kirsanov, D., Belikova, V., Ageev, V., Usenov, I., Galyanin, V., Minet, O., Sakharova, T., Danielyan, G., Feliksberger, E., & Artyushenko, V. (2017). Development and Testing of an LED-Based Near-Infrared Sensor for Human Kidney Tumor Diagnostics. Sensors (Basel), 17(8). https://doi.org/10.3390/s17081914

Gelse, K., Korber, L., Schone, M., Raum, K., Koch, P., Pachowsky, M., Welsch, G., & Breiter, R. (2017). Transplantation of Chemically Processed Decellularized Meniscal Allografts. Cartilage, 8(2), 180-190. https://doi.org/10.1177/1947603516646161

Potsika, V. T., Protopappas, V. C., Grivas, K. N., Gortsas, T. V., Raum, K., Polyzos, D. K., & Fotiadis, D. I. (2017). Numerical evaluation of the backward propagating acoustic field in healing long bones. J Acoust Soc Am, 142(2), 962. https://doi.org/10.1121/1.4998722

Rohrbach, D., Inkinen, S. I., Zatloukalova, J., Kadow-Romacker, A., Joukainen, A., Malo, M. K., Mamou, J., Toyras, J., & Raum, K. (2017). Regular chondrocyte spacing is a potential cause for coherent ultrasound backscatter in human articular cartilage. J Acoust Soc Am, 141(5), 3105. https://doi.org/10.1121/1.4979339

Schone, M., Schulz, R. M., Tzschatzsch, H., Varga, P., & Raum, K. (2017). Ultrasound palpation for fast in-situ quantification of articular cartilage stiffness, thickness and relaxation capacity. Biomech Model Mechanobiol, 16(4), 1171-1185. https://doi.org/10.1007/s10237-017-0880-z

 

2016

Bernard, S., Schneider, J., Varga, P., Laugier, P., Raum, K., & Grimal, Q. (2016). Elasticity-density and viscoelasticity-density relationships at the tibia mid-diaphysis assessed from resonant ultrasound spectroscopy measurements. Biomech Model Mechanobiol, 15(1), 97-109. https://doi.org/10.1007/s10237-015-0689-6

Hesse, B., Salome, M., Castillo-Michel, H., Cotte, M., Fayard, B., Sahle, C. J., De Nolf, W., Hradilova, J., Masic, A., Kanngiesser, B., Bohner, M., Varga, P., Raum, K., & Schrof, S. (2016). Full-Field Calcium K-Edge X-ray Absorption Near-Edge Structure Spectroscopy on Cortical Bone at the Micron-Scale: Polarization Effects Reveal Mineral Orientation. Anal Chem, 88(7), 3826-3835. https://doi.org/10.1021/acs.analchem.5b04898

Mannicke, N., Schone, M., Liukkonen, J., Fachet, D., Inkinen, S., Malo, M. K., Oelze, M. L., Toyras, J., Jurvelin, J. S., & Raum, K. (2016). Species-Independent Modeling of High-Frequency Ultrasound Backscatter in Hyaline Cartilage. Ultrasound Med Biol, 42(6), 1375-1384. https://doi.org/10.1016/j.ultrasmedbio.2016.01.018

Padilla, F., Puts, R., Vico, L., Guignandon, A., & Raum, K. (2016). Stimulation of Bone Repair with Ultrasound. Adv Exp Med Biol, 880, 385-427. https://doi.org/10.1007/978-3-319-22536-4_21

Penta, R., Raum, K., Grimal, Q., Schrof, S., & Gerisch, A. (2016). Can a continuous mineral foam explain the stiffening of aged bone tissue? A micromechanical approach to mineral fusion in musculoskeletal tissues. Bioinspir Biomim, 11(3), 035004. https://doi.org/10.1088/1748-3190/11/3/035004

Puts, R., Albers, J., Kadow-Romacker, A., Geissler, S., & Raum, K. (2016). Influence of Donor Age and Stimulation Intensity on Osteogenic Differentiation of Rat Mesenchymal Stromal Cells in Response to Focused Low-Intensity Pulsed Ultrasound. Ultrasound Med Biol, 42(12), 2965-2974. https://doi.org/10.1016/j.ultrasmedbio.2016.08.012

Puts, R., Rikeit, P., Ruschke, K., Kadow-Romacker, A., Hwang, S., Jenderka, K. V., Knaus, P., & Raum, K. (2016). Activation of Mechanosensitive Transcription Factors in Murine C2C12 Mesenchymal Precursors by Focused Low-Intensity Pulsed Ultrasound (FLIPUS). IEEE Trans Ultrason Ferroelectr Freq Control, 63(10), 1505-1513. https://doi.org/10.1109/TUFFC.2016.2586972

Puts, R., Ruschke, K., Ambrosi, T. H., Kadow-Romacker, A., Knaus, P., Jenderka, K. V., & Raum, K. (2016). A Focused Low-Intensity Pulsed Ultrasound (FLIPUS) System for Cell Stimulation: Physical and Biological Proof of Principle. IEEE Trans Ultrason Ferroelectr Freq Control, 63(1), 91-100. https://doi.org/10.1109/TUFFC.2015.2498042

Schone, M., Mannicke, N., Somerson, J. S., Marquass, B., Henkelmann, R., Mochida, J., Aigner, T., Raum, K., & Schulz, R. M. (2016). 3D ultrasound biomicroscopy for assessment of cartilage repair tissue: volumetric characterisation and correlation to established classification systems. Eur Cell Mater, 31, 119-135. https://doi.org/10.22203/ecm.v031a09

Schrof, S., Varga, P., Hesse, B., Schone, M., Schutz, R., Masic, A., & Raum, K. (2016). Multimodal correlative investigation of the interplaying micro-architecture, chemical composition and mechanical properties of human cortical bone tissue reveals predominant role of fibrillar organization in determining microelastic tissue properties. Acta Biomater, 44, 51-64. https://doi.org/10.1016/j.actbio.2016.08.001

Potsika, V., Gortsas, T., Iori, G., V, C. P., Raum, K., Polyzos, D., & D, I. F. (2016). Computational Study of the Effect of Cortical Porosity on Ultrasound Wave Propagation in Healthy and Osteoporotic Long Bones. Materials (Basel), 9(3). https://doi.org/10.3390/ma9030205

 

2015

Amitai, I., Werner, S., Schicke, B., Burmester, G. R., Minet, O., Zabarylo, U., Backhaus, M., & Ohrndorf, S. (2015). Comparison of Photo Optical Imaging with Musculoskeletal Ultrasound and Clinical Examination in the Assessment of Inflammatory Activity in Proximal Interphalangeal Joints in Rheumatoid Arthritis and Osteoarthritis. J Rheumatol, 42(9), 1595-1602. https://doi.org/10.3899/jrheum.150098

Bernal, A., Perez, L. M., De Lucas, B., Martin, N. S., Kadow-Romacker, A., Plaza, G., Raum, K., & Galvez, B. G. (2015). Low-Intensity Pulsed Ultrasound Improves the Functional Properties of Cardiac Mesoangioblasts. Stem Cell Rev Rep, 11(6), 852-865. https://doi.org/10.1007/s12015-015-9608-6

Checa, S., Hesse, B., Roschger, P., Aido, M., Duda, G. N., Raum, K., & Willie, B. M. (2015). Skeletal maturation substantially affects elastic tissue properties in the endosteal and periosteal regions of loaded mice tibiae. Acta Biomater, 21, 154-164. https://doi.org/10.1016/j.actbio.2015.04.020

Granke, M., Grimal, Q., Parnell, W. J., Raum, K., Gerisch, A., Peyrin, F., Saied, A., & Laugier, P. (2015). To what extent can cortical bone millimeter-scale elasticity be predicted by a two-phase composite model with variable porosity? Acta Biomater, 12, 207-215. https://doi.org/10.1016/j.actbio.2014.10.011

Hesse, B., Varga, P., Langer, M., Pacureanu, A., Schrof, S., Mannicke, N., Suhonen, H., Maurer, P., Cloetens, P., Peyrin, F., & Raum, K. (2015). Canalicular network morphology is the major determinant of the spatial distribution of mass density in human bone tissue: evidence by means of synchrotron radiation phase-contrast nano- CT . J Bone Miner Res, 30(2), 346-356. https://doi.org/10.1002/jbmr.2324

Potsika, V. T., Grivas, K. N., Gortsas, T., Protopappas, V. C., Polyzos, D. K., Raum, K., & Fotiadis, D. I. (2015). Ultrasound propagation in cortical bone: Axial transmission and backscattering simulations. Annu Int Conf IEEE Eng Med Biol Soc, 2015, 1456-1459. https://doi.org/10.1109/EMBC.2015.7318644

Rohrbach, D., Grimal, Q., Varga, P., Peyrin, F., Langer, M., Laugier, P., & Raum, K. (2015). Distribution of mesoscale elastic properties and mass density in the human femoral shaft. Connect Tissue Res, 56(2), 120-132. https://doi.org/10.3109/03008207.2015.1013627

Varga, P., Hesse, B., Langer, M., Schrof, S., Mannicke, N., Suhonen, H., Pacureanu, A., Pahr, D., Peyrin, F., & Raum, K. (2015). Synchrotron X-ray phase nano-tomography-based analysis of the lacunar-canalicular network morphology and its relation to the strains experienced by osteocytes in situ as predicted by case-specific finite element analysis. Biomech Model Mechanobiol, 14(2), 267-282. https://doi.org/10.1007/s10237-014-0601-9

 

2014

Grimal, Q., Rohrbach, D., Grondin, J., Barkmann, R., Gluer, C. C., Raum, K., & Laugier, P. (2014). Modeling of femoral neck cortical bone for the numerical simulation of ultrasound propagation. Ultrasound Med Biol, 40(5), 1015-1026. https://doi.org/10.1016/j.ultrasmedbio.2013.11.010

Hesse, B., Langer, M., Varga, P., Pacureanu, A., Dong, P., Schrof, S., Mannicke, N., Suhonen, H., Olivier, C., Maurer, P., Kazakia, G. J., Raum, K., & Peyrin, F. (2014). Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron microCT study. PLoS One, 9(2), e88481. https://doi.org/10.1371/journal.pone.0088481

Hesse, B., Mannicke, N., Pacureanu, A., Varga, P., Langer, M., Maurer, P., Peyrin, F., & Raum, K. (2014). Accessing osteocyte lacunar geometrical properties in human jaw bone on the submicron length scale using synchrotron radiation muCT. J Microsc, 255(3), 158-168. https://doi.org/10.1111/jmi.12147

Kuhnisch, J., Seto, J., Lange, C., Schrof, S., Stumpp, S., Kobus, K., Grohmann, J., Kossler, N., Varga, P., Osswald, M., Emmerich, D., Tinschert, S., Thielemann, F., Duda, G., Seifert, W., El Khassawna, T., Stevenson, D. A., Elefteriou, F., Kornak, U.,  Kolanczyk, M. (2014). Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1. PLoS One, 9(1), e86115. https://doi.org/10.1371/journal.pone.0086115

Langer, M., Cloetens, P., Hesse, B., Suhonen, H., Pacureanu, A., Raum, K., & Peyrin, F. (2014). Priors for X-ray in-line phase tomography of heterogeneous objects. Philos Trans A Math Phys Eng Sci, 372(2010), 20130129. https://doi.org/10.1098/rsta.2013.0129

Mannicke, N., Schone, M., Gottwald, M., Gobel, F., Oelze, M. L., & Raum, K. (2014). 3-D high-frequency ultrasound backscatter analysis of human articular cartilage. Ultrasound Med Biol, 40(1), 244-257. https://doi.org/10.1016/j.ultrasmedbio.2013.08.015

Mannicke, N., Schone, M., Oelze, M., & Raum, K. (2014). Articular cartilage degeneration classification by means of high-frequency ultrasound. Osteoarthritis Cartilage, 22(10), 1577-1582. https://doi.org/10.1016/j.joca.2014.06.019

Padilla, F., Puts, R., Vico, L., & Raum, K. (2014). Stimulation of bone repair with ultrasound: a review of the possible mechanic effects. Ultrasonics, 54(5), 1125-1145. https://doi.org/10.1016/j.ultras.2014.01.004

Petter-Puchner, A., Gruber-Blum, S., Walder, N., Fortelny, R. H., Redl, H., & Raum, K. (2014). Ultrasound biomicroscopy (UBM) and scanning acoustic microscopy (SAM) for the assessment of hernia mesh integration: a comparison to standard histology in an experimental model. Hernia, 18(4), 579-585. https://doi.org/10.1007/s10029-013-1201-9

Potsika, V. T., Grivas, K. N., Protopappas, V. C., Vavva, M. G., Raum, K., Rohrbach, D., Polyzos, D., & Fotiadis, D. I. (2014). Application of an effective medium theory for modeling ultrasound wave propagation in healing long bones. Ultrasonics, 54(5), 1219-1230. https://doi.org/10.1016/j.ultras.2013.09.002

Raum, K., Grimal, Q., Varga, P., Barkmann, R., Gluer, C. C., & Laugier, P. (2014). Ultrasound to assess bone quality. Curr Osteoporos Rep, 12(2), 154-162. https://doi.org/10.1007/s11914-014-0205-4

Rohde, K., Rohrbach, D., Gluer, C. C., Laugier, P., Grimal, Q., Raum, K., & Barkmann, R. (2014). Influence of porosity, pore size, and cortical thickness on the propagation of ultrasonic waves guided through the femoral neck cortex: a simulation study. IEEE Trans Ultrason Ferroelectr Freq Control, 61(2), 302-313. https://doi.org/10.1109/TUFFC.2014.6722615

Schrof, S., Varga, P., Galvis, L., Raum, K., & Masic, A. (2014). 3D Raman mapping of the collagen fibril orientation in human osteonal lamellae. J Struct Biol, 187(3), 266-275. https://doi.org/10.1016/j.jsb.2014.07.001

Tiburtius, S., Schrof, S., Molnar, F., Varga, P., Peyrin, F., Grimal, Q., Raum, K., & Gerisch, A. (2014). On the elastic properties of mineralized turkey leg tendon tissue: multiscale model and experiment. Biomech Model Mechanobiol, 13(5), 1003-1023. https://doi.org/10.1007/s10237-013-0550-8

 

2013

Granke, M., Gourrier, A., Rupin, F., Raum, K., Peyrin, F., Burghammer, M., Saied, A., & Laugier, P. (2013). Microfibril orientation dominates the microelastic properties of human bone tissue at the lamellar length scale. PLoS One, 8(3), e58043. https://doi.org/10.1371/journal.pone.0058043

Malo, M. K., Rohrbach, D., Isaksson, H., Toyras, J., Jurvelin, J. S., Tamminen, I. S., Kroger, H., & Raum, K. (2013). Longitudinal elastic properties and porosity of cortical bone tissue vary with age in human proximal femur. Bone, 53(2), 451-458. https://doi.org/10.1016/j.bone.2013.01.015

Rohrbach, D., Preininger, B., Hesse, B., Gerigk, H., Perka, C., & Raum, K. (2013). The early phases of bone healing can be differentiated in a rat osteotomy model by focused transverse-transmission ultrasound. Ultrasound Med Biol, 39(9), 1642-1653. https://doi.org/10.1016/j.ultrasmedbio.2013.03.028

Schone, M., Mannicke, N., Gottwald, M., Gobel, F., & Raum, K. (2013). 3-d high-frequency ultrasound improves the estimation of surface properties in degenerated cartilage. Ultrasound Med Biol, 39(5), 834-844. https://doi.org/10.1016/j.ultrasmedbio.2012.10.010

Varga, P., Pacureanu, A., Langer, M., Suhonen, H., Hesse, B., Grimal, Q., Cloetens, P., Raum, K., & Peyrin, F. (2013). Investigation of the three-dimensional orientation of mineralized collagen fibrils in human lamellar bone using synchrotron X-ray phase nano-tomography. Acta Biomater, 9(9), 8118-8127. https://doi.org/10.1016/j.actbio.2013.05.015

 

2012

Lakshmanan, S., Koch, T., Brand, S., Mannicke, N., Wicke, M., Morlein, D., & Raum, K. (2012). Prediction of the intramuscular fat content in loin muscle of pig carcasses by quantitative time-resolved ultrasound. Meat Sci, 90(1), 216-225. https://doi.org/10.1016/j.meatsci.2011.07.004

Preininger, B., Hesse, B., Rohrbach, D., Varga, P., Gerigk, H., Langer, M., Peyrin, F., Perka, C., & Raum, K. (2012). Histogram feature-based classification improves differentiability of early bone healing stages from micro-computed tomographic data. J Comput Assist Tomogr, 36(4), 469-476. https://doi.org/10.1097/RCT.0b013e31825eae8a

Rohrbach, D., Lakshmanan, S., Peyrin, F., Langer, M., Gerisch, A., Grimal, Q., Laugier, P., & Raum, K. (2012). Spatial distribution of tissue level properties in a human femoral cortical bone. J Biomech, 45(13), 2264-2270. https://doi.org/10.1016/j.jbiomech.2012.06.003

 

2011

Grimal, Q., Raum, K., Gerisch, A., & Laugier, P. (2011). A determination of the minimum sizes of representative volume elements for the prediction of cortical bone elastic properties. Biomech Model Mechanobiol, 10(6), 925-937. https://doi.org/10.1007/s10237-010-0284-9

Koch, T., Lakshmanan, S., Brand, S., Wicke, M., Raum, K., & Morlein, D. (2011a). Ultrasound velocity and attenuation of porcine soft tissues with respect to structure and composition: I. Muscle. Meat Sci, 88(1), 51-58. https://doi.org/10.1016/j.meatsci.2010.12.002

Koch, T., Lakshmanan, S., Brand, S., Wicke, M., Raum, K., & Morlein, D. (2011b). Ultrasound velocity and attenuation of porcine soft tissues with respect to structure and composition: II. Skin and backfat. Meat Sci, 88(1), 67-74. https://doi.org/10.1016/j.meatsci.2010.12.004

Preininger, B., Checa, S., Molnar, F. L., Fratzl, P., Duda, G. N., & Raum, K. (2011). Spatial-temporal mapping of bone structural and elastic properties in a sheep model following osteotomy. Ultrasound Med Biol, 37(3), 474-483. https://doi.org/10.1016/j.ultrasmedbio.2010.12.007

 

2010

Gelse, K., Olk, A., Eichhorn, S., Swoboda, B., Schoene, M., & Raum, K. (2010). Quantitative ultrasound biomicroscopy for the analysis of healthy and repair cartilage tissue. Eur Cell Mater, 19, 58-71. https://doi.org/10.22203/ecm.v019a07

Minet, O., Scheibe, P., & Zabarylo, U. J. (2010). Diagnosis of rheumatoid arthritis using light: correction of motion artefacts and color visualization of multispectral images. J Biophotonics, 3(3), 130-137. https://doi.org/10.1002/jbio.200900092

Rupin, F., Bossis, D., Vico, L., Peyrin, F., Raum, K., Laugier, P., & Saied, A. (2010). Adaptive remodeling of trabecular bone core cultured in 3-D bioreactor providing cyclic loading: an acoustic microscopy study. Ultrasound Med Biol, 36(6), 999-1007. https://doi.org/10.1016/j.ultrasmedbio.2010.03.004

 

1998 – 2009

Ruschke, K., Ebelt, H., Kloting, N., Boettger, T., Raum, K., Bluher, M., & Braun, T. (2009). Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice. PLoS One, 4(5), e5516. https://doi.org/10.1371/journal.pone.0005516

Grimal, Q., Raum, K., Gerisch, A., & Laugier, P. (2008). Derivation of the mesoscopic elasticity tensor of cortical bone from quantitative impedance images at the micron scale. Comput Methods Biomech Biomed Engin, 11(2), 147-157. https://doi.org/10.1080/10255840802296913

Leicht, S., & Raum, K. (2008). Acoustic impedance changes in cartilage and subchondral bone due to primary arthrosis. Ultrasonics, 48(6-7), 613-620. https://doi.org/10.1016/j.ultras.2008.04.012

Raum, K. (2008). Microelastic imaging of bone. IEEE Trans Ultrason Ferroelectr Freq Control, 55(7), 1417-1431. https://doi.org/10.1109/TUFFC.2008.817

Saied, A., Raum, K., Leguerney, I., & Laugier, P. (2008). Spatial distribution of anisotropic acoustic impedance assessed by time-resolved 50-MHz scanning acoustic microscopy and its relation to porosity in human cortical bone. Bone, 43(1), 187-194. https://doi.org/10.1016/j.bone.2008.02.015

Lakshmanan, S., Bodi, A., & Raum, K. (2007). Assessment of anisotropic tissue elasticity of cortical bone from high-resolution, angular acoustic measurements. IEEE Trans Ultrason Ferroelectr Freq Control, 54(8), 1560-1570. https://doi.org/10.1109/tuffc.2007.426

Raum, K., Hofmann, T., Leguerney, I., Saied, A., Peyrin, F., Vico, L., & Laugier, P. (2007). Variations of microstructure, mineral density and tissue elasticity in B6/C3H mice. Bone, 41(6), 1017-1024. https://doi.org/10.1016/j.bone.2007.08.042

Raum, K., Kempf, K., Hein, H. J., Schubert, J., & Maurer, P. (2007). Preservation of microelastic properties of dentin and tooth enamel in vitro--a scanning acoustic microscopy study. Dent Mater, 23(10), 1221-1228. https://doi.org/10.1016/j.dental.2006.11.009

Hofman, T., Raum, K., Leguerney, I., Saied, A., Peyrin, F., Vico, L., & Laugier, P. (2006). Assessment of bone structure and acoustic impedance in C3H and BL6 mice using high resolution scanning acoustic microscopy. Ultrasonics, 44 Suppl 1, e1307-1311. https://doi.org/10.1016/j.ultras.2006.05.032

Hofmann, T., Heyroth, F., Meinhard, H., Franzel, W., & Raum, K. (2006). Assessment of composition and anisotropic elastic properties of secondary osteon lamellae. J Biomech, 39(12), 2282-2294. https://doi.org/10.1016/j.jbiomech.2005.07.009

Hube, R., Mayr, H., Hein, W., & Raum, K. (2006). Prediction of biomechanical stability after callus distraction by high resolution scanning acoustic microscopy. Ultrasound Med Biol, 32(12), 1913-1921. https://doi.org/10.1016/j.ultrasmedbio.2006.06.010
 

Raum, K., Leguerney, I., Chandelier, F., Talmant, M., Saied, A., Peyrin, F., & Laugier, P. (2006). Site-matched assessment of structural and tissue properties of cortical bone using scanning acoustic microscopy and synchrotron radiation muCT. Phys Med Biol, 51(3), 733-746. https://doi.org/10.1088/0031-9155/51/3/017

Raum, K., Cleveland, R. O., Peyrin, F., & Laugier, P. (2006). Derivation of elastic stiffness from site-matched mineral density and acoustic impedance maps. Phys Med Biol, 51(3), 747-758. https://doi.org/10.1088/0031-9155/51/3/018

Raum, K., Leguerney, I., Chandelier, F., Bossy, E., Talmant, M., Saied, A., Peyrin, F., & Laugier, P. (2005). Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements. Ultrasound Med Biol, 31(9), 1225-1235. https://doi.org/10.1016/j.ultrasmedbio.2005.05.002

Raum, K., Reisshauer, J., & Brandt, J. (2004). Frequency and resolution dependence of the anisotropic impedance estimation in cortical bone using time-resolved scanning acoustic microscopy. J Biomed Mater Res A, 71(3), 430-438. https://doi.org/10.1002/jbm.a.30156

Raum, K., Ozguler, A., Morris, S. A., & O'Brien, W. R. (1998). Channel defect detection in food packages using integrated backscatter ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control, 45(1), 30-40. https://doi.org/10.1109/58.646905